An autoimmune disease is when your immune system mistakenly attacks your body. The immune system protects the body against germs, bacteria, and viruses. When it senses foreign invaders, it sends an army of fighting cells to attack them. The immune system may tell the difference between foreign cells and its cells.
In an autoimmune disease, the immune system wrongs parts of your body, such as joints or skin, for a foreign invader and releases proteins called autoantibodies that attack healthy cells. Some autoimmune diseases target only one organ.
Type 1 diabetes detriments the pancreas. Other diseases, like systemic lupus erythematosus (SLE), modify the entire body.
There are over 80 different autoimmune diseases. Here we will introduce 10 of the most common ones:
Rheumatism is an inflammatory autoimmune disease that affects the knees, joints, and wrists. The symptoms of this disease are usually seen on both sides of the body and include the following:
Environmental and genetic factors play a role in rheumatism. This disease is more common among women, the elderly, those who smoke, and obese people.
Doctors use disease-modifying anti-rheumatic drugs to treat rheumatoid arthritis. These drugs slow down the progression of the disease and prevent the deformity of the joints.
Other treatment options include biologics, corticosteroids, and nonsteroidal anti-inflammatory drugs.
Lupus attacks the skin, joints, blood vessels, or internal organs and causes inflammation.
Systemic Lupus Erythematosus (SLE) is the most prevalent and severe type of this disorder that affects multiple organs. People with lupus may experience periods of remission and flare-ups.
The most apparent feature of lupus disorder is the butterfly-shaped rash on the face, cheeks, and nose.
Related: “Skin Blemishes To Worry About“
Common symptoms include fatigue, pain, joint swelling, fever, and skin rashes. Lupus can also cause the following problems:
Genetic, hormonal, and environmental factors can cause lupus.
Potential environmental triggers for this disease include fatigue, stress, infection, and exposure to the sun’s ultraviolet rays.
Related: “ How To Prevent Sunburn Without Sunscreen?“
Some medications (such as sulfa drugs) may lead to lupus flares. Some side effects of sulfa drugs are sensitivity to sunlight, reduction of blood cells, and skin rashes.
The goal of treating lupus disorder is to reduce pain and inflammation. Corticosteroids are prescribed to suppress inflammation, and antimalarial drugs are prescribed to prevent relapse.
Aspirin, ibuprofen, or acetaminophen may also be helpful.
Related: “What Is The Difference Between Intermittent, Remittent, And Relapsing Fever?“
Skin cells usually grow and are shed when they are no longer needed. Psoriasis reasons skin cells to multiply too rapidly.
The extra cells build up and form red, inflamed patches, usually plaques with silvery-white scales on the skin. Up to 30% of people with psoriasis also experience swelling, stiffness, and joint pain. This form of the disease is called psoriatic arthritis.
Multiple sclerosis, or MS, is a condition in which autoantibodies attack the myelin sheath that covers nerves and is essential for proper functioning.
This disease may have different symptoms depending on the specific area of the affected nervous system, including vision problems, sensory disturbances such as numbness and tingling, bladder problems, weakness, loss of coordination, and tremors.
There is no particular diagnostic test for MS; However, your doctor will use a few different tests to help diagnose it, such as:
Evoked potential (a test that examines the response of the nervous system)
Lumbar puncture (cerebrospinal fluid examination)
MRI
Early symptoms of MS may be more physical, while later symptoms affect a person’s mood or cognition. Some factors, such as genetics, Epstein-Barr virus (EBV), and environmental factors, increase the risk of expanding this disease.
There is no definitive cure for MS, but available solutions can help in the following cases:
Corticosteroids, immunomodulators, muscle relaxants, anticonvulsants, and supportive care are all treatments for MS.
Your thyroid is a small gland in the front of your neck that regulates various functions. This gland produces thyroid hormone, which controls metabolism, heart rate, temperature, mood, and more.
Hashimoto’s thyroiditis is the most common reason for hypothyroidism because it destroys the cells of the thyroid gland and reduces hormone production.
Symptoms include fatigue, weight gain, constipation, hair loss, or a slow heart rate. Of course, people with Hashimoto’s thyroiditis may not have any symptoms at first.
People with celiac disease, lupus, rheumatoid arthritis, Sjogren’s syndrome, or type 1 diabetes may be at risk for developing Hashimoto’s thyroiditis; a family history of this disease can increase the probability of getting this disorder.
Treatment of Hashimoto’s thyroiditis requires regular visits to the doctor. Many patients have to use levothyroxine.
In people with this disease, the immune system attacks the thyroid gland, but instead of destroying thyroid cells, it leads to the overproduction of hormones.
Graves’ disease is the most common reason of hyperthyroidism and causes the following symptoms:
Many people with Graves’ autoimmune disease have problems such as swelling or bulging of the eyes. In rare cases, the condition causes redness and thickening of the skin on the legs and tops of the feet.
Genes, hormones, and environmental factors, including stress, pregnancy, and infection, play a role in developing Graves’ disease. Antithyroid drugs are usually given to these patients.
Surgery or using radioactive iodine to destroy thyroid cells may be recommended in other cases. If you do either of these options, you will need to take thyroid hormone to replace what your body no longer makes.
This disease is a disorder in which the skin loses its color and white spots appear on the skin. These spots may be less than 5 mm or larger. If there is hair in the vitiligo area, it will turn white or gray.
Vitiligo occurs when melanin is not produced due to a disorder and weakness of the body’s immune system, and as a result, the skin loses its color. In other words, attacking melanin cells destroys them.
People between the ages of 10 and 30 are usually affected by this disease.
Related: “ What Causes Skin Pigmentation Disorder?“
Alopecia areata is a common reason for hair loss and usually causes round bald areas on the scalp. However, this disease may also affect the eyebrows, eyelashes, genital area, and armpits.
Other names for this disorder are local tinea capitis and nervous tinea capitis.
Alopecia is an autoimmune disease, and this condition is caused by the fact that the immune system of the individual’s body does not recognize the hair follicle as its own and treats it as a stranger.
The immune response created by the body often results in patchy hair loss on the scalp.
T lymphocytes are integrated around the affected follicle and cause inflammation and subsequent hair loss. In this case, the damage to the hair follicle is not permanent.
This problem can affect people of all ages, and it often starts in childhood and may be seen in the family.
A few cases of babies born with congenital regional tinea versicolor have also been recorded. However, these cases are not considered autoimmune diseases because the baby’s immune system is not fully developed.
One type of inflammatory bowel disease (IBD) is the autoimmune disease Crohn’s disease, which causes your digestive tract to become inflamed and irritated. If you have Crohn’s, you may experience symptoms such as abdominal pain, diarrhea, weight loss, and rectal bleeding.
It is a lifelong disease that cannot be cured. However, Crohn’s disease treatments usually control your symptoms and allow you to lead an active life. Crohn’s disease is a lifelong inflammatory bowel disease (IBD).
This disease inflames and irritates the digestive system – especially the small and large intestines. Crohn’s disease can cause diarrhea and stomach cramps. Sometimes it flares up.
Crohn’s disease is named by the American gastroenterologist Dr. Burrill Crohn (1884-1983). He was one of the first doctors to describe this disease in 1932. Ulcerative colitis is another commonly diagnosed inflammatory bowel disease.
Related: “Symptoms Of A Failing Liver“
When people with this autoimmune disease consume gluten (a protein in wheat, rye, and barley), their immune system attacks and detriments the small intestine; As a result, absorption of nutrients in the gut is reduced, which can be detrimental to health in the long run.
Celiac disease usually runs in families. If a person’s father, mother, child, sister, or brother suffers from this disease, there is a 4-15% chance that he will also be affected by this disorder.
Celiac causes gastrointestinal symptoms in children, such as bloating, vomiting, chronic diarrhea, or constipation. Gastrointestinal symptoms are less common in adults. Adults may experience fatigue, anemia, menstrual irregularities, or osteoporosis symptoms.
When people’s immune system acts against their body, they get autoimmune diseases. Some diseases are easily treated, while others impose a problematic treatment process on the patient.
Some autoimmune diseases stay with a person for the rest of their life; unfortunately, some are fatal. Autoimmune diseases are one of the ten prominent reasons for death in women of all ages (up to age 64).
Some experts believe that the food you consume can be effective in the occurrence or process of autoimmune diseases; in addition, doing physical exercises can be impressive in controlling the symptoms of the disease.
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Dr. Majid Zohrabi started treating his patients in Dubai in 2022 and continues his activities in private medical centers in the UAE.
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